Commands

This is not an exhaustive list, keep in mind that you can alsways use sm_help in the console to check for all commands available to you.

To reduce the number of things you have to bind to key, screaming MEDIC is equal to pressing +use.
You can also pick up weapons from the ground with +use or +use_action_slot_item (default H); Drag props around with your hands and +attack2 (default RMB); Bring up an interaction menu with other players and interact with NPCs (+use); Steal NPCs money (+attack3 ; +crouch and +use) if cops are online.

Roleplay Plugin:
/dropweapon, /dropitDrop the weapon you're currently holding (or use dropitem bind, default L)
/hands, /holsterPut your weapons away and show hands
/clanShows clan menu
/cTalk to your clan members
/clanname <name>Sets the name of the clan you are leader in
/buydoorBuys door pointing at and existing sub doors
/selldoorAsks to sell Door pointing at and existing sub doors, within menu
/givekeysShows Give Keys menu of Door pointing at
/takekeys, /deletekeysShows Take Keys menu of Door pointing at
/doorinfoShows info. in console of Door pointing at
/doorname <name>Sets the name of Door pointing at
/door, /doormenuShows menu of Door pointing at
/removelocksRemoves all locks from Door pointing at and adds them back to inventory
/lockdoor //lockitLocks or unlocks the door pointed, provided you're allowed to (or use +attack3, default MMB)
/freezeitFreezes and saves furniture inside your homezone
/unfreezeitUnfreezes furniture inside your homezone. Marks furniture for deletion again
/deleteitUnsave and delete furniture you spawned
/colorit <Red> <Green> <Blue> <Alpha>Changes the color of your furniture. Requires 4 values: Red Green Blue Alpha
/itemsShows inventory menu
/useitem <id> [amount=1]Uses an item by database id. Amount is 1 by default
/itemlist [page=1]Shows all items in console in ascending order
/joblistShows list of all jobs in console
/jobinfoPrints current job info
/jobmenuShows job types menu
/plantPlants a weed pot if being a Drug Addict
/kill, /stuckAll killbinds have a 10 second cooldown to prevent cheap escape from pvp!
/rtd, /rollthedice, /dice [#userid|name]Rolls the Dice on the player given or looking at, if not specified
/rprank [#userid|name]Shows Roleplay statistics for a given player or yourself, if not specified
/thetimeDisplay the server time and time left to map reset
/call <#userid|name>Calls a player in-game
/answerAnswers to all receiving calls
/hangupplayer <#userid|name>Hangs up phone on a player (even if only calling)
/hangupHangs up phone on everyone (even if only calling)
/enablephoneAllows receiving calls on phone
/disablephoneDisallows receiving calls on phone and hangs up on everyone on phone (even if only calling)
/talkShows talk menu to say predefined HL2 phrases
/sms <#userid|name> <message>Sends a private message to a client
/r <message>Answers a private message sent to/by you earlier